The wonders of a 400 MHz HTS magnet NMR system, how it works and our results at Amgen

Maria Victoria Silva Elipe Ph.D.

Department of Attribute Sciences, Amgen Inc.

April 8th 5pm EST

Amgen 360 Binney St, Cambridge, MA 02141

Happy Hour Sponsored by SciY/MestreC

This will be a hybrid event. The speaker will be on line but we would like to get the community to get together in person. We highly encourage members to join us at Amgen.

‍ ‍Abstract

The discovery of new ceramic materials containing Ba-La-Cu oxides in 1986 exhibiting superconductive properties at high temperatures (35 K or higher), opened a new world of opportunities for NMRs and MRIs to move away from liquid cryogens, recognized with the Nobel Prize in Physics in 1987. A prototype 400 MHz high temperature superconducting (HTS) power-driven magnet NMR spectrometer was installed at Amgen’s chemistry laboratory to be tested for a variety of applications, structure analysis, reaction monitoring, and CASE-3D studies with RDCs. The HTS “cryofree” magnet does not required liquid cryogens refills and has a smaller footprint than a comparable low temperature superconducting (LTS) magnet, with stability as the unknown factor of this technology. Our evaluation of its performance was successful.

To Volunteer as a speaker please contact us atinfo@NEWNMR.org